Medullary thyroid carcinoma: a 30-year experience at one institution in Korea
Annals of Surgical Treatment and Research
;
: 278-287, 2016.
Article
Dans Anglais
| WPRIM
| ID: wpr-89529
ABSTRACT
PURPOSE:
The objective of this study was to review the clinical outcome and prognosis of patients with sporadic and hereditary medullary thyroid cancer (MTC) who were treated at a single tertiary hospital in Korea.METHODS:
We retrospectively reviewed the case files of 85 patients treated from August 1982 to February 2012.RESULTS:
In all, 65 patients (76.5%) had sporadic MTC and 20 patients (23.5%) had hereditary MTC. Patients in the sporadic group were older than in the hereditary group (P < 0.001). However, the hereditary group had more tumor multiplicity (P < 0.001) and bilaterality (P < 0.001). Neither survival rate was significantly different between the sporadic and hereditary groups (P = 0.775 and P = 0.866). By multivariate analysis, distant metastasis was a significant prognostic factor for overall and progression-free survival.CONCLUSION:
In general, patients with MTC have favorable outcomes. Distant metastasis appears to be the strongest predictor of overall and progression-free survival.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pronostic
/
Glande thyroide
/
Tumeurs de la thyroïde
/
Analyse multifactorielle
/
Taux de survie
/
Études rétrospectives
/
Survie sans rechute
/
Centres de soins tertiaires
/
Corée
/
Métastase tumorale
Type d'étude:
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Humains
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Annals of Surgical Treatment and Research
Année:
2016
Type:
Article
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