Advance in Electroencephalographic and Imaging Studies in Depression Children and Adolescents (review) / 中国康复理论与实践

ABSTRACT

Studies with electroencephalography, transcranial Doppler (TCD), magnetic resonance, positron emission tomography (PET), and single-photon emission computed tomography (SPECT) have achieved some positive results for depression in children and adolescents. Electroencephalographic studies found that the patients' α, β, δ, θ waves, and P300, P200, N100 and N200 in event-related potential (ERP) were significantly different from typical ones, and cortical activation area was uneven. TCD, magnetic resonance, PET and SPECT studies found that the patients with depression occurred cerebral blood flow abnormalities in frontal lobe and temporal lobe. Magnetic resonance studies found that there were brain structural and metabolic abnormalities in frontal lobe, left fusiform gyrus and anterior cingulate cortex, and N-acetyl aspartate, creatine, choline and glutamate might be a part of the cause of depression.