Advances on the correlation between hypoxia inducible factor-1α and acute lung injury / 国际儿科学杂志

ABSTRACT

Acute lung injury is an inflammatory pulmonary disease with complex pathogenesis, frequently resulting in systematic hypoxia.As a central regulator modulating cellular oxygen levels, hypoxia reducible factor-1α affects the development of acute lung injury, which also has been gaining focus as a potential therapeutic target of acute lung injury.Therefore, hypoxia reducible factor-1α is a pivotal factor while understanding the pathogenesis and exploring the therapeutic approach of acute lung injury.