Research progress on clinical trials of radiaotherapy and chemotherapy in localized pancreatic cancer / 中华放射肿瘤学杂志

ABSTRACT

Pancreatic cancer is technically divided into surgically resectable, borderline resectable or unresectable disease according to the relationship between tumor mass and adjacent blood vessels. Upon diagnosis, most of the lesions have been locally advanced or had distant metastases, and only 20% of the patients have the opportunity for tumor resection. Radiotherapy and chemotherapy are essential for pancreatic cancer. In this article, the literatures published in recent years were reviewed to focus on the research progress on the clinical trials of neoadjuvant radiochemotherapy, stereotactic body radiation therapy (SBRT), radiochemotherapy combined with immunotherapy for localized pancreatic cancer.