Early Pathological Changes after Stereotactic Radiosurgery for AVM

ABSTRACT

The effects of radiosurgery on the arteriovenous malformation(AVM) nidus are documented in some studies as endothelial hypertrophy followed by obliteration of the vascular lumen with thrombosis. According to the literature total angiographic obliteration of the AVM nidus after radiosurgery takes about two years, but few reports of the histologic changes after radiosurgery for AVM are found. The authors encountered a case in which AVM surgery was performed after three months of LINAC radiosurgery because of the AVM bleeding. Histologic changes seen in the AVM nidus after three months of radiosurgery were the endothelial hypertrophy and the perivascular inflammation as early features of obliteration.