Systematic review with meta-analysis: Non-alcoholic fatty liver disease and the association with pregnancy outcomes
Clinical and Molecular Hepatology
;
: 52-66, 2022.
Article
Dans Anglais
| WPRIM
| ID: wpr-913980
ABSTRACT
Background/Aims@#Maternal and fetal outcomes in pregnant patients with Non-alcoholic fatty liver disease (NAFLD) have been largely unexplored. To determine the level of evidence associated with maternal and fetal outcomes in pregnant women with NAFLD. @*Methods@#We conducted a comprehensive literature search. The studies included pregnant patients with a previous, current or subsequent diagnosis of NAFLD. We used a random-effects model using odds ratios (OR) with 95% confidence intervals (CI). @*Results@#Twenty-two studies, with 13,641 female NAFLD patients were reviewed. The results highlight that NAFLD patients had a statistically significant increased likelihood of baseline diabetes mellitus (OR, 6.00; 95% CI, 2.21–16.31; P0.05). @*Conclusions@#This meta-analysis provides pooled evidence that NAFLD is associated with a substantial increase in maternal diabetic and hypertensive complications and multiple adverse fetal outcomes. This data is important for clinicians managing these patients before, during and after pregnancy.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Revues systématiques évaluées
langue:
Anglais
Texte intégral:
Clinical and Molecular Hepatology
Année:
2022
Type:
Article
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