Undifferentiated Carcinoma with Osteoclast-Like Giant Cells of the Pancreas Mimicking a Predominantly Calcified Mass: Case Report and Literature Review

ABSTRACT

Undifferentiated carcinoma with osteoclast-like giant cells (UCOGCs) of the pancreas is a rare neoplasm that contains osteoclast-like giant cells, which are morphologically identical to those seen in giant cell tumors of bones. Histopathologically, it is composed of round to spindle-shaped neoplastic cells and non-neoplastic histiocytic giant cells. Although only limited radiologic findings are available due to the rarity of this tumor, UCOGCs shows variable imaging features in the literature from an inhomogeneous solid mass to a multilocular cystic tumor. Herein, we report an unusual manifestation of UCOGCs of the pancreas mimicking a predominantly calcified mass with radiologic-pathologic correlation.