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Application of platelet-rich fibrin on mandibular third molar extraction: systematic review and Meta-analysis / 华西口腔医学杂志
Article de En | WPRIM | ID: wpr-921381
Bibliothèque responsable: WPRO
ABSTRACT
OBJECTIVES@#This study aims to analyze the effectiveness of platelet-rich fibrin (PRF) in mandibular third molar extraction and provide suggestions for alleviating postoperative complications.@*METHODS@#Pubmed, EMBASE, Web of Science, and SinoMed were searched electronically on February 2020. Randomized controlled trials focusing on PRF usage in mandibular third molar extraction were included. Reviewers assessed the risk of bias in the included literature and extracted data independently using the criteria recommended by the Cochrane Collaboration. Meta-analysis was performed using RevMan 5.3 and STATA 13.0.@*RESULTS@#Twenty-one studies were included, comprising 991 patients who had mandibular third molar extraction. The topical application of PRF effectively reduced pain after extraction [MD=-12.06, 95%CI (-21.42, -2.71), @*CONCLUSIONS@#Limited clinical evidence indicates that applying PRF after mandibular third molar extraction could reduce pain, swelling, trismus and the occurrence of dry socket and promote soft tissue healing. However, the effect of PRF on bone healing requires further large-scale randomized controlled trials and unified measurement criteria.
Sujet(s)
Mots clés
Texte intégral: 1 Indice: WPRIM Sujet Principal: Extraction dentaire / Dent enclavée / Fibrine riche en plaquettes / Mandibule / Dent de sagesse Type d'étude: Clinical_trials / Systematic_reviews Limites du sujet: Humans langue: En Texte intégral: West China Journal of Stomatology Année: 2021 Type: Article
Texte intégral: 1 Indice: WPRIM Sujet Principal: Extraction dentaire / Dent enclavée / Fibrine riche en plaquettes / Mandibule / Dent de sagesse Type d'étude: Clinical_trials / Systematic_reviews Limites du sujet: Humans langue: En Texte intégral: West China Journal of Stomatology Année: 2021 Type: Article