Advances in the release mechanisms of bluetongue virus / 生物工程学报
Chinese Journal of Biotechnology
; (12): 3179-3189, 2021.
Article
de Zh
| WPRIM
| ID: wpr-921415
Bibliothèque responsable:
WPRO
ABSTRACT
Bluetongue virus (BTV) causes Bluetongue (BT) of ruminants vectored by culicoides midges. It is also a classic model for studying the release mechanism of non-enveloped virus. This review begins with the infection and assembly of BTV, then summarizes the advances of different ways of releasing BTV. This includes BTV-induced autophagy and the release as extracellular vesicles via multivesicular bodies, BTV-induced apoptosis and the lytic release, as well as different pathways of release through budding via plasma membrane. The regulatory mechanisms of NS3 which is a key non-structural protein during the release of BTV are also discussed, providing a basis for further understanding the molecular mechanisms underpinning the infection, proliferation and release of BTV.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Ovis
/
Ceratopogonidae
/
Protéines virales non structurales
/
Fièvre catarrhale du mouton
/
Virus de la langue bleue
Limites du sujet:
Animals
langue:
Zh
Texte intégral:
Chinese Journal of Biotechnology
Année:
2021
Type:
Article