Hb Bart's Quantitative Analysis in the Screening of α-Thalassemia / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 1903-1906, 2021.
Article
de Zh
| WPRIM
| ID: wpr-922221
Bibliothèque responsable:
WPRO
ABSTRACT
OBJECTIVE@#To research the relationship between difference types of α-thalassemia gene types and Hb Bart's hemoglobin bands.@*METHODS@#Capillary electrophoresis was used to screen thalassemia gene for the newborn form January 2020 to December 2020, and the thalassemia gene was detected by PCR or PCR-NGS in the positive patients. The relationship between α-thalassemia gene and Hb Bart's hemoglobin was compared and analyzed statistically.@*RESULTS@#There were significant differences in Hb Bart's hemoglobin among the different α-thalassemia mutation types, Hb Bart's was the highest in --SEA/-α@*CONCLUSION@#The Hb Bart's content of different genotypes of α-thalassemia are significantly different. The Hb Bart's content shows high application value in α-thalassemia screening and genotyping identification.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Hémoglobines anormales
/
Réaction de polymérisation en chaîne
/
Alpha-Thalassémie
/
Hétérozygote
Type d'étude:
Diagnostic_studies
/
Screening_studies
Limites du sujet:
Humans
/
Newborn
langue:
Zh
Texte intégral:
Journal of Experimental Hematology
Année:
2021
Type:
Article