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Clinical values of cerebral oxygen saturation monitoring in patients with septic shock / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences) ; (12): 1212-1219, 2021.
Article Dans Anglais | WPRIM | ID: wpr-922604
ABSTRACT
OBJECTIVES@#Sepsis associated encephalopathy (SAE) is a common neurological complication of sepsis. Delirium is a common symtom of SAE. The pathophysiology of SAE is still unclear, but several likely mechanisms have been proposed, such as mitochondrial and endothelial dysfunction, neurotransmission disturbances, derangements of calcium homeostasis, cerebral microcirculation dysfunction, and brain hypoperfusion. Near-infrared spectroscopy (NIRS) is a non-invasive measure for regional cerebral oxygen saturation (rSO@*METHODS@#A total of 48 septic patients who admitted to the intensive care unit (ICU) of Xiangya Hospital, Central South University from August 2017 to May 2018, were retrospectively study. Septic shock was diagnosed according to the criteria of sepsis 3.0 defined by the American Association of Critical Care Medicine and the European Society of Critical Care Medicine. NIRS monitoring was performed during the first 6 hours admitted to ICU with sensors placed on the bilateral forehead of patients. The maximum (rSO@*RESULTS@#The overall 28-day mortality of septic shock patients was 47.92% (23/48), and the incidence of delirium was 18.75% (9/48). The rSO@*CONCLUSIONS@#Cerebral anoxia and hyperoxia, as well as the large fluctuation of cerebral oxygen saturation are important factors that affect the outcomes and the incidence of delirium in septic shock patients, which should be paid attention to in clinical practice. Dynamic monitoring of cerebral oxygen saturation and maintain its stability may be of great significance in patients with septic shock.
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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Pronostic / Choc septique / Études rétrospectives / Sepsie / Indice APACHE / Saturation en oxygène / Unités de soins intensifs Type d'étude: Étude observationnelle / Étude pronostique / Facteurs de risque Limites du sujet: Humains langue: Anglais Texte intégral: Journal of Central South University(Medical Sciences) Année: 2021 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Pronostic / Choc septique / Études rétrospectives / Sepsie / Indice APACHE / Saturation en oxygène / Unités de soins intensifs Type d'étude: Étude observationnelle / Étude pronostique / Facteurs de risque Limites du sujet: Humains langue: Anglais Texte intégral: Journal of Central South University(Medical Sciences) Année: 2021 Type: Article