Cecal Cancer with Xanthogranulomatous Inflammation

ABSTRACT

Xanthogranulomatous inflammation is a chronic inflammatory condition characterized by aggregation of lipid-laden foamy macrophages (xanthoma cells). This disease entity is well- recognized in the kidney and gallbladder. However, involvement of the colon is extremely rare. Radiologically, xanthogranulomatous inflammation could be misinterpreted as a locally invasive cancerous lesion. Indeed, coexisting malignancy has been reported in xanthogranulomatous inflammation. In this case report, a woman complained of fever and right lower quadrant abdominal pain for a period of 5 days. A huge mass lesion with severe pericolic infiltration was found on abdominal CT scan. Right hemicolectomy was performed along with removal of the adjacent soft tissue and right ovary and fallopian tube. Pathology examination demonstrated xanthogranulomatous inflammation coexisting with cecal cancer (T3N0M0).