Advance in Drug Development for Alzheimer's Disease Targeted Microtuble Associated Protein Tau (review) / 中国康复理论与实践
Chinese Journal of Rehabilitation Theory and Practice
; (12): 240-244, 2014.
Article
de Zh
| WPRIM
| ID: wpr-927176
Bibliothèque responsable:
WPRO
ABSTRACT
@#Alzheimer's disease (AD) is the general neurodegenerative disease in the elderly. Alterations of microtubule associated protein tau are closely related to the onset and progression of AD. The role of tau protein in the development of AD has been a focus in the current study of AD, with an emphasis on the identification of compounds that inhibit tau protein phosphorylation and aggregate, and accelerate tau protein depolymerization. The current research status of tau protein as target of AD preventive and therapeutic drug was also reviewed.
Texte intégral:
1
Indice:
WPRIM
langue:
Zh
Texte intégral:
Chinese Journal of Rehabilitation Theory and Practice
Année:
2014
Type:
Article