Application and population control strategy of microbial modular co-culture engineering / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 1421-1431, 2022.
Article
Dans Chinois
| WPRIM
| ID: wpr-927790
ABSTRACT
Traditional methods of microbial synthesis usually rely on a single engineered strain to synthesize the target product through metabolic engineering. The key cofactors, precursors and energy are produced by the introduced complex synthetic pathways. This would increase the physiological burden of engineering strains, resulting in a decrease in the yield of target products. The modular co-culture engineering has become an attractive solution for effective heterologous biosynthesis, where product yield can be greatly improved. In the modular co-culture engineering, the coordination between the population of different modules is essential for increasing the production efficiency. This article summarized recent advances in the application of modular co-culture engineering and population control strategies.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Régulation démographique
/
Techniques de coculture
/
Génie métabolique
langue:
Chinois
Texte intégral:
Chinese Journal of Biotechnology
Année:
2022
Type:
Article
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