The effect of CYP2C19 genetic polymorphism on proton pump inhibitors and the efficacy of Hp eradication in children / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 19-23, 2022.
Article
Dans Chinois
| WPRIM
| ID: wpr-929796
ABSTRACT
The polymorphism of CYP2C19 gene constitutes the basis for the difference in enzyme activity and affects the metabolism of many drugs including proton pump inhibitors.The distribution of CYP2C19 gene varies by region and race.The study on the relationship between CYP2C19 genotype and proton pump inhibitors is of great significance for the individualized treatment of Helicobacter pylori (Hp) in children.This paper reviews the effects of CYP2C19 gene polymorphism on proton pump inhibitors and the efficacy of Hp eradication in children.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
International Journal of Pediatrics
Année:
2022
Type:
Article
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