Research progress of regulation relationship between aerobic glycolysis and Wnt/β-catenin pathway in breast cancer / 国际外科学杂志
International Journal of Surgery
;
(12): 861-864, 2021.
Article
Dans Chinois
| WPRIM
| ID: wpr-929958
ABSTRACT
Breast cancer as one of the common malignant tumors in women, has received widespread attention. Aerobic glycolysis is the main metabolic pathway of breast cancer cells, and its key enzymes play an important role in the metabolism of cancer cells. The key enzymes of glycolysis are regulated by the Wnt/β-catenin signaling pathway. Abnormal activation of the Wnt/β-catenin signaling pathway regulates downstream target genes, thereby affecting the activities of key glycolysis enzymes. Glycolysis and Wnt/β-catenin signaling pathway play an important role in the occurrence and development of breast cancer, but the specific regulatory relationship between the two has not been studied in depth. Therefore, this article summarizes the regulation relationship between aerobic glycolysis and Wnt/β-catenin pathway in order to explore new strategies for breast cancer treatment.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
International Journal of Surgery
Année:
2021
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS