Takotsubo syndrome in children / 中国小儿急救医学

ABSTRACT

Takotsubo syndrome (TTS) is an acute and mostly reversible cardiomyopathy that mimics an acute coronary syndrome with systolic dysfunction of left ventricular.Although supraphysiological epinephrine levels have been associated with TTS, the detailed pathophysiology is incompletely understood.According to the distribution of left ventricular wall motion abnormalities, various morphological subtypes have been identified.The ultimate diagnosis depends on cardiac imaging with left ventricular angiography during acute heart catheterization, as well as echocardiography and cardiac magnetic resonance.Management is based on observational data, while randomized multicenter studies are still lacking.Mechanical circulatory support is an emerging strategy for patients with TTS and shock, in order to avoid catecholamines and inotropes in particular.This review provides a general overview of TTS.However, the demographic characteristics, diagnosis, treatment and prognosis of TTS have not been well studied in children.