The role of the gut microbiota in the pathogenesis of sarcopenia / 中华老年医学杂志
Chinese Journal of Geriatrics
; (12): 605-609, 2022.
Article
de Zh
| WPRIM
| ID: wpr-933131
Bibliothèque responsable:
WPRO
ABSTRACT
Sarcopenia is a progressive syndrome associated with aging, generalized loss of skeletal muscle mass, muscle strength and function.It is closely related to the occurrence of adverse events such as ambulatorydysfunction, falls and fractures in the elderly, and seriously affects the quality of life of the elderly.The etiology of sarcopenia has not been fully elucidated.Various pathophysiological mechanisms such as reduced exercise, genetic factors, age-related hormone changes, malnutrition and insufficient protein intake, decreased neuromuscular function, pro-inflammatory cytokines, and myocyte apoptosis are possible factors.Recent studies have found that intestinal microecological changes may be implicated in the occurrence and development of sarcopenia.In this article, we reviewed intestinal microecological changes and their possible role in the mechanisms underlying sarcopenia.
Texte intégral:
1
Indice:
WPRIM
Type d'étude:
Etiology_studies
langue:
Zh
Texte intégral:
Chinese Journal of Geriatrics
Année:
2022
Type:
Article