Significance of combination of targeted therapy and immunotherapy in conversion therapy of biliary tract cancer / 中华外科杂志
Chinese Journal of Surgery
;
(12): 343-350, 2022.
Article
Dans Chinois
| WPRIM
| ID: wpr-935609
ABSTRACT
Biliary tract cancer has insidious onset and high degree of malignancy, and radical resection is often impossible when it is diagnosed.Conversion therapy can achieve tumor downgrading, so that patients who were initially unresectable have a chance to achieve R0 resection.However, due to the high heterogeneity and complex immune microenvironment of biliary tract cancer, conversion therapy is still in the stage of active exploration.As a new type of conversion therapy, combination of targeted therapy and immunotherapy is of great significance to effectively improve the efficiency of conversion therapy.Further exploration of combination mechanism and improvement of immune microenvironment are expected to become the future direction of combination of targeted therapy and immunotherapy.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Tumeurs des voies biliaires
/
Protocoles de polychimiothérapie antinéoplasique
/
Association thérapeutique
/
Microenvironnement tumoral
/
Gastrectomie
/
Immunothérapie
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Chinese Journal of Surgery
Année:
2022
Type:
Article
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