Research advances in the treatment of liver failure with mesenchymal stem cell-derived exosomes / 中华肝脏病杂志
Chinese Journal of Hepatology
;
(12): 249-252, 2022.
Article
Dans Chinois
| WPRIM
| ID: wpr-935936
ABSTRACT
Liver failure is a serious clinical syndrome in which multiple pathogenic factors exceed the liver's self-repair capability, resulting massive hepatocellular necrosis, rapid disease progression and high mortality. Liver transplantation is the most effective method for the treatment of liver failure, but it has disadvantages, such as insufficient liver donor and high cost. The clinical efficacy of mesenchymal stem cells in liver failure have been validated, but its application has been limited to certain extent. Cell-free-based therapies, especially mesenchymal stem cell-derived exosomes, has become a research hotspot in recent years. This paper reviews the research advances in the treatment of liver failure with the use of mesenchymal stem cell-derived exosomes.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Défaillance hépatique aigüe
/
Défaillance hépatique
/
Insuffisance hépatique
/
Exosomes
/
Cellules souches mésenchymateuses
/
Thérapie cellulaire et tissulaire
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Chinese Journal of Hepatology
Année:
2022
Type:
Article
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