MicroRNA-126 inhibits the proliferation of lung cancer cell line A549
Asian Pacific Journal of Tropical Medicine
; (12): 239-242, 2015.
Article
Dans Zh
| WPRIM
| ID: wpr-951529
Responsable en Bibliothèque :
WPRO
ABSTRACT
Objective: To study the role of microRNA-126 in the development of lung cancer. Methods: The biological function of microRNA-126 was detected using EdU assay and CCK-8 assay; the target gene of microRNA-126 was analyzed using real time RT-PCR and Western blot assay. Results: In A549 cell line, overexpression of microRNA-126 inhibits the proliferation rate; VEGF is the target gene of microRNA-126; microRNA-126 exerts its function via regulating VEGF protein level. Conclusions: microRNA-126 inhibits the proliferation in A549 cell line.
Texte intégral:
1
Indice:
WPRIM
langue:
Zh
Texte intégral:
Asian Pacific Journal of Tropical Medicine
Année:
2015
Type:
Article