Research progress of the exosomes in diagnosis and treatment of central nervous system diseases / 中华实用儿科临床杂志

ABSTRACT

Exosomes are some small membrane-bound vesicles released by cells into extracellular spaces.They carry a variety of bioactive molecules, such as proteins, RNA and lipids for material exchange and communication in cells.Exosomes have been recognized as an important pathway in the nervous system in both normal and disease settings.Meanwhile, exosomes can pass through the blood-brain barrier.Therefore, exosomes provide a new strategy for the diagnosis and treatment of central nervous system diseases.In this review, general characteristics of exosomes, pathological and physiological functions of exosomes in central nervous systems and the progress of exosomes applied to the diagnosis and treatment of central nervous system diseases are discussed.