Efficacy of the Troponin T Rapid Assay Kit in Early Diagnosis of Acute Myocardial Infarction
Korean Circulation Journal
;
: 1116-1121, 1995.
Article
Dans Coréen
| WPRIM
| ID: wpr-9547
ABSTRACT
BACKGROUND:
In the diagnosis of acute myocardial infarction, measurement of CK-MB is widely used as an enzyme test, but it needs special instruments, lacks specificity in the presence of concomitant skeletal muscle injuries, and has narrow diagnostic time window. Cardiac specific troponin T-a new marker for the diagnosis of myocardial injury-is now available. Besides the quantitative assay, rapid qualitative asay is also possible with the development of rapid assay Kit. We studied about the efficacy of the Troponin T rapid assay Kit in early doagnosis of actue myocardial infarction in the emergency room.METHODS:
Total Ck, Ck-MB, LDH and serum troponin T activities were determined when the patients arrived at the emergency room and at the same time Troponin T rapid assay kit test was done. Final diagnosis was made through the serial measurement of CK, CK-MB and LDH. Diagnostic efficacy of each rest was evaluated.RESULTS:
Overall diagnostic sensitivity and specificity of Troponin T rapid assay kit were 0.97 and 0.91. When evaluated only with the initial results, Troponin T rapid assay kit showed sensitivity 0.87, specificity 0.97, serum troponin T 0.75, 0.92, and Ck-Mb 0.81,0.95. In one patient who was finally diagnosed as a septic shock, Ck-MB was elevated but serum troponin T was not and Troponin T rapid assay kit test showed negative result.CONCLUSION:
Troponin T rapid assay kit test seems to show nearly the same sensitivity and specificity in diagnosis of acute myocardial infarction compared to CK-MB. This test can be done simply and easily in a short time. Thus, with the use of this test, morbidity, mortality and economic loss due to misdiagnosis and delay of diagnosis of myocardial infarction might be reduced.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Choc septique
/
Troponine
/
Mortalité
/
Sensibilité et spécificité
/
Muscles squelettiques
/
Troponine T
/
Diagnostic précoce
/
Diagnostic
/
Erreurs de diagnostic
/
Service hospitalier d'urgences
Type d'étude:
Etude diagnostique
/
Étude pronostique
/
Recherche qualitative
/
Étude de dépistage
Limites du sujet:
Humains
langue:
Coréen
Texte intégral:
Korean Circulation Journal
Année:
1995
Type:
Article
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