Levosulpiride-induced Parkinsonim
Journal of the Korean Neurological Association
; : 418-421, 2003.
Article
Dans Ko
| WPRIM
| ID: wpr-95810
Responsable en Bibliothèque :
WPRO
ABSTRACT
The present report discusses four cases of chronic renal failure, which developed symptoms of parkinsonism in response to levosulpiride. The temporal relationship between levosulpiride discontinuation and the disappearance of parkinsonism suggests a causal link. In addition, decreased striatal dopamine transporter bindings assessed by [I-123] IPT SPECT were observed in two patients suggesting that a dopamine blocking agent causes the dysfunction of nigrostriatal dopaminergic neurons and that such injury may be involved in the pathogenesis of drug-induced parkinsonism.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Dopamine
/
Tomographie par émission monophotonique
/
Syndromes parkinsoniens
/
Transporteurs de la dopamine
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Neurones dopaminergiques
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Défaillance rénale chronique
Limites du sujet:
Humans
langue:
Ko
Texte intégral:
Journal of the Korean Neurological Association
Année:
2003
Type:
Article