Intra-nasal mass presenting with Cushing's syndrome and CSF rhinorrhea: A case report
Philippine Journal of Surgical Specialties
;
: 20-24, 2017.
Article
Dans Anglais
| WPRIM
| ID: wpr-959824
ABSTRACT
@#<p style="text-align justify;">This is a case of a 47 year-old female presenting with typical Cushingoid appearance and CSF rhinorrhea. MRI revealed a 4.4 cm x 2.9 cm x 4.5 cm enhancing intranasal mass with evidence of erosion of the left cribriform extending to the left anterior cranial fossa. Dexamethasone suppression test yielded elevated cortisol level. Endoscopic nasal biopsy done showed a round cell tumor positive for ACTH, synaptophysin, chromogranin A, and S-100. Patient subsequently underwent endoscopic endonasal excision of left intranasal mass with creation of pericranial flap for repair of CSF leak. This report is presented to discuss a rare case of ACTH secreting esthesioneurblastoma including its diagnostic challenges and surgical options for repair of anterior cranial fossa defect to address CSF leak particularly by means of a vascularized pericranial flap.</p>
Recherche sur Google
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Lambeaux chirurgicaux
/
Dexaméthasone
/
Hydrocortisone
/
Nez
/
Rhinorrhée cérébrospinale
/
Synaptophysine
/
Hormone corticotrope
/
Fosse crânienne antérieure
/
Endoscopie
/
Chromogranine A
Limites du sujet:
Femelle
/
Humains
langue:
Anglais
Texte intégral:
Philippine Journal of Surgical Specialties
Année:
2017
Type:
Article
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