Flow Cytometric Analysis of Lymphocyte Subpopulations of Cattle Infected with Bovine Leukemia Virus
Journal of Bacteriology and Virology
;
: 165-173, 2005.
Article
Dans Coréen
| WPRIM
| ID: wpr-9650
ABSTRACT
We examined lymphocyte subpopulations of peripheral blood from BLV infected and noninfected Holstein-Friesian dairy cattle reared in Korea by flow cytometry using monoclonal antibodies specifically reactive with bovine leukocyte differentiation marker. Lymphocyte subpopulations expressing BoCD11b, B-B2, CD5, B, MHC II-DP, MHC II-DQ, and MHC II-DR antigens were significantly abundant in the BLV(+) group than the BLV(-) group (p<0.01). On double staining, subpopulation of B-1a(BoCD5+ BoCD11b+) lymphocytes was significantly increased in leukemic group. However, T-lymphocyte lineage expressing BoCD2, BoCD4, BoCD8, and WC1 antigens was significantly lower than in the BLV(+) group (p<0.01). However the absolute number of T-lymphocytes expressing BoCD2, BoCD4, BoCD8, and WC1 antigens in BLV(+) group remained with in the normal range. Furthermore mean ratio of BoCD4/BoCD8 in the BLV(+) groups was higher than that in the BLV(-) group. Taken together, cellular immune responses did not seem to significantly be decreased in the leukemic cattle.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Valeurs de référence
/
Lymphocytes
/
Lymphocytes T
/
Sous-populations de lymphocytes
/
Leucose bovine enzootique
/
Virus de la leucémie bovine
/
Cytométrie en flux
/
Immunité cellulaire
/
Corée
/
Leucocytes
Limites du sujet:
Animaux
Pays comme sujet:
Asie
langue:
Coréen
Texte intégral:
Journal of Bacteriology and Virology
Année:
2005
Type:
Article
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