Interferon-alpha in the Treatment of Behcet's Disease
Journal of the Korean Ophthalmological Society
;
: 1674-1680, 2004.
Article
Dans Coréen
| WPRIM
| ID: wpr-97116
ABSTRACT
PURPOSE:
To determine the therapeutic efficacy of interferon-alpha on patients with Behcet's disease who have been resistant to conventional therapies.METHODS:
We treated 22 eyes of 13 patients with interferon-alpha for a mean of 20.5 months. They were given 3 million units interferon-alpha subcutaneously three times a week. Using slit lamp microscopy, fluorescent angiography, the authors compared visual acuity, frequency of relapse of uveitis and complications of interferon-alpha.RESULTS:
The average ocular attack rate fell from 0.41 times a month to 0.19 times after interferon therapy. In addition, the degree of intraocular inflammation and especially retinal vasculitis decreased. There were no side effects significant enough to stop using interferon.CONCLUSIONS:
Therapy with interferon-alpha seems to be an effective and safe regimen in Behcet's disease for refractory ocular attack and for the protection of vision.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Récidive
/
Uvéite
/
Angiographie
/
Acuité visuelle
/
Interférons
/
Interféron alpha
/
Vascularite rétinienne
/
Inflammation
/
Microscopie
Limites du sujet:
Humains
langue:
Coréen
Texte intégral:
Journal of the Korean Ophthalmological Society
Année:
2004
Type:
Article
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