Influence of α-Zearalanol on lipometabolism and hemorheology in experimental hyperlipidemia rabbits / 中国康复理论与实践
Chinese Journal of Rehabilitation Theory and Practice
;
(12): 924-926, 2005.
Article
Dans Chinois
| WPRIM
| ID: wpr-979508
ABSTRACT
@#ObjectiveTo investigate the effect of α-Zearalanol(α-ZAL) on lipometabolism and hemorheology in ovariectomized(OVX) hyperlipidemia rabbits.Methods44 adult virgin female rabbits were divided into 5 groups,group A normal control;group B sham+CHO;group C OVX+CHO;group D OVX+CHO+17βE_2;group E OVX+CHO+α-ZAL.Cholesterol(CHO) was fed to rabbits for 12 weeks.Before and after feeding CHO,the serum lipid(TC,TG,LDL-C,HDL-C) were measured;Blood viscosity,plasma viscosity,aggregation index of RBC(AIRC) and fibrinogen were also assayed respectively.ResultsThe serum levels of TC,TG and LDL-C in group B and E were significantly decreased compared with those in group C(P<0.05);the level of blood viscosity,plasma viscosity and AIRC platelet aggregation rate in group D and E were also significantly decreased compared with those in group C(P<0.05).Conclusionα-ZAL can improve vascular function through the adjustment of lipometabolism and hemorheology.
Recherche sur Google
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Journal of Rehabilitation Theory and Practice
Année:
2005
Type:
Article
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