Neuroprotective potential of cannabidiol: Molecular mechanisms and clinical implications / 中西医结合学报
Journal of Integrative Medicine
;
(12): 236-244, 2023.
Article
Dans Anglais
| WPRIM
| ID: wpr-982677
ABSTRACT
Cannabidiol (CBD), a nonpsychotropic phytocannabinoid that was once largely disregarded, is currently the subject of significant medicinal study. CBD is found in Cannabis sativa, and has a myriad of neuropharmacological impacts on the central nervous system, including the capacity to reduce neuroinflammation, protein misfolding and oxidative stress. On the other hand, it is well established that CBD generates its biological effects without exerting a large amount of intrinsic activity upon cannabinoid receptors. Because of this, CBD does not produce undesirable psychotropic effects that are typical of marijuana derivatives. Nonetheless, CBD displays the exceptional potential to become a supplementary medicine in various neurological diseases. Currently, many clinical trials are being conducted to investigate this possibility. This review focuses on the therapeutic effects of CBD in managing neurological disorders like Alzheimer's disease, Parkinson's disease and epilepsy. Overall, this review aims to build a stronger understanding of CBD and provide guidance for future fundamental scientific and clinical investigations, opening a new therapeutic window for neuroprotection. Please cite this article as Tambe SM, Mali S, Amin PD, Oliveira M. Neuroprotective potential of Cannabidiol Molecular mechanisms and clinical implications. J Integr Med. 2023; 21(3) 236-244.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Cannabidiol
/
Cannabinoïdes
/
Cannabis
/
Neuroprotecteurs
/
Épilepsie
/
Neuroprotection
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Journal of Integrative Medicine
Année:
2023
Type:
Article
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