A study on the expression of VEGF in the blunt injury of rat's skin / 法医学杂志
Journal of Forensic Medicine
; (6): 13-15, 2003.
Article
de Zh
| WPRIM
| ID: wpr-982960
Bibliothèque responsable:
WPRO
ABSTRACT
OBJECTIVE@#To evaluate changes of VEGF in skin after blunt injury.@*METHODS@#The rats of injury groups were subjected to skin blunt injury by free-falling iron hammer. The samples taken at 1 h, 3 h, 6 h, 12 h, 1 d, 3 d, 5 d, 7 d, 9 d after injury were studied by immunohistochemistry and MIAS image analysis system.@*RESULTS@#In the skin of normal control group the expression level of VEGF was low. The increase of VEGF could be observed at 1 day after injury, reached peak at 7 days and declined at 9 days.@*CONCLUSION@#Blunt injury in the skin could induce the expression of the VEGF. Moreover, the change pattern of VEGF level was quite regular with time and could be used to estimate the time after skin injury.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Peau
/
Facteurs temps
/
Plaies non pénétrantes
/
Facteurs de croissance endothéliale
/
Lymphokines
/
Rat Sprague-Dawley
/
Protéines et peptides de signalisation intercellulaire
/
Facteurs de croissance endothéliale vasculaire
/
Facteur de croissance endothéliale vasculaire de type A
/
Médecine légale
Limites du sujet:
Animals
langue:
Zh
Texte intégral:
Journal of Forensic Medicine
Année:
2003
Type:
Article