Bcl-2 expression following the brain concussion in rats / 法医学杂志

ABSTRACT

OBJECTIVE@#To evaluate the expression of Bcl-2 protein after brain concussion.@*METHODS@#Expression levels of Bel-2 protein in cortex, pontine and cerebellum of rats were investigated using immunohistochemistry.@*RESULTS@#There was no expression of Bcl-2 protein in control group seen. The expression of Bcl-2 protein in brain concussion groups was detected at l hour, and the expression level reached its peak 4 days after the concussion and then declined gradually.@*CONCLUSION@#Our findings suggest that the detection of Bel-2 protein could be an indicator for diagnosis of brain concussion and for estimation of the post injury time interval.