Sequence polymorphism of mtDNA control region in Chinese Qinghai Tibetan ethnic group and Han population / 法医学杂志
Journal of Forensic Medicine
;
(6): 417-422, 2008.
Article
Dans Chinois
| WPRIM
| ID: wpr-983419
ABSTRACT
OBJECT@#To study sequence polymorphism of mtDNA control region in Chinese Qinghai Tibetan group and Han population.@*METHODS@#Venous blood samples from 69 unrelated Qinghai Tibetans and Han individuals were collected and their mtDNA control region sequences were analyzed. Polymorphism indicators were calculated. The genetic distances based on Fst and Rst among eleven groups from different districts include the Qinghai Tibetan and Han population were elucidated using Nei's method. Phylogenetic tree was constructed.@*RESULTS@#There were 56 polymorphic loci and 59 loci found in the mtDNA control region of Tibetan group and Han population, respectively. It was indicated by the Rst distance that there was a far distance between Qinghai Tibetan and the other populations (P<0.05), and the distance was much closer between Qinghai Han and Xi'an Han, Mongolian, Changsha Han populations (P>0.05).@*CONCLUSION@#There is unique genetic polymorphism of mtDNA control region both in Qinghai Tibetan and Han population. These findings may be useful in forensic identification, population genetic and migration studies.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Phylogenèse
/
Polymorphisme génétique
/
ADN mitochondrial
/
Chine
/
Analyse de séquence d'ADN
/
Tibet
/
Asiatiques
/
Génétique légale
Limites du sujet:
Humains
Pays comme sujet:
Asie
langue:
Chinois
Texte intégral:
Journal of Forensic Medicine
Année:
2008
Type:
Article
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