Effects of cocaine on activities of ATPase, LDH and SDH in mouse splenocytes / 法医学杂志
Journal of Forensic Medicine
;
(6): 81-83, 2010.
Article
Dans Chinois
| WPRIM
| ID: wpr-983543
ABSTRACT
OBJECTIVE@#To examine the effects of cocaine on the activities of ATPase, LDH and SDH in cultured mouse splenocytes in vitro.@*METHODS@#The ATPase, LDH and SDH activities in mouse splenocytes were detected at day 7 after continuous culturing the mouse cells exposed to cocaine hydrochloride in final concentration of 10, 20 and 100 microg/mL in vitro.@*RESULTS@#The activities of ATPase, LDH and SDH in mouse splenocytes exposed to cocaine hydrochloride in final concentration of 10, 20 and 100 microg/mL were significantly decreased after continuous culturing for 7 days.@*CONCLUSION@#The present study demonstrated that cocaine could inhibit the activities of ATPase, LDH and SDH in cultured splenocytes in vitro.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Rate
/
Succinate Dehydrogenase
/
Cellules cultivées
/
Cocaïne
/
Adenosine triphosphatases
/
Relation dose-effet des médicaments
/
L-Lactate dehydrogenase
/
Lignées consanguines de souris
Limites du sujet:
Animaux
langue:
Chinois
Texte intégral:
Journal of Forensic Medicine
Année:
2010
Type:
Article
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