Calculation of likelihood ratio for X-STR typing in kinship testing / 法医学杂志
Journal of Forensic Medicine
;
(6): 180-184, 2013.
Article
Dans Chinois
| WPRIM
| ID: wpr-983816
ABSTRACT
OBJECTIVE@#To deduce the calculation formulae of likelihood ratio for kinship testing with X-short tandem repeat (X-STR) typing.@*METHODS@#With the identity by decent coefficient of different relationships, the joint genotypic probability of two individuals with specific genotypes was calculated as X value, and then the joint genotypic probability of two unrelated individuals was calculated as Y value; therefore, the likelihood ratio value (X/Y) was obtained.@*RESULTS@#The calculation formulae of the likelihood ratio for different genotype combinations of the female-female, female-male and male-male genetic relationships were derived and verified by real cases.@*CONCLUSION@#The calculation formulae are simple and accurate to evaluate the likelihood ratio for two individuals' genetic relationship with X-STR typing. The formulae provide the basic potential value for the difficult kinship testing with X-STR loci.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Algorithmes
/
Fonctions de vraisemblance
/
Réaction de polymérisation en chaîne
/
Répétitions microsatellites
/
Chromosomes X humains
/
Allèles
/
Génétique légale
/
Fréquence d'allèle
/
Génotype
Limites du sujet:
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Journal of Forensic Medicine
Année:
2013
Type:
Article
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