Renal Denervation for Chronic Heart Failure: Background and Pathophysiological Rationale
Korean Circulation Journal
; : 9-15, 2017.
Article
de En
| WPRIM
| ID: wpr-98383
Bibliothèque responsable:
WPRO
ABSTRACT
The activation of the sympathetic nervous system is associated with cardiovascular hospitalizations and death in heart failure. Renal denervation has been shown to effectively reduce sympathetic overdrive in certain patients with uncontrolled hypertension. Pilot trials investigating renal denervation as a potential treatment approach for heart failure were initiated. Heart failure comorbidities like obstructive sleep apnea, metabolic syndrome and arrhythmias could also be targets for renal denervation, because these occurrences are also mediated by the activation of the sympathetic nervous system. Therefore, renal denervation in heart failure is worthy of further investigation, although its effectiveness still has to be proven. Herein, we describe the pathophysiological rationale and the effect of renal denervation on surrogates of the heart failure syndrome.
Mots clés
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Troubles du rythme cardiaque
/
Système nerveux sympathique
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Comorbidité
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Syndrome d'apnées obstructives du sommeil
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Dénervation
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Coeur
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Défaillance cardiaque
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Hospitalisation
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Hypertension artérielle
Limites du sujet:
Humans
langue:
En
Texte intégral:
Korean Circulation Journal
Année:
2017
Type:
Article