Gitelman's Syndrome Associated with Chondrocalcinosis
Journal of Rheumatic Diseases
;
: 266-270, 2016.
Article
Dans Anglais
| WPRIM
| ID: wpr-98405
ABSTRACT
Gitelman's syndrome (GS), a hereditary disease characterized by hypokalemia, hypomagnesemia, and hypocalciuria, is a salt-losing renal tubulopathy. Herein, we describe a case of a 28-year-old woman diagnosed with atypical GS accompanying chondrocalcinosis. One year ago, she presented with vomiting, hypokalemic metabolic alkalosis, and hypocalciuria, and was tested by diuretic challenge test. As a result, she was diagnosed with atypical GS with normomagnesemia and treated with spironolactone and potassium supplementation. Meanwhile, acute arthritis of the right 1st metatarsophalangeal joint occurred. On the radiographies of the knees, chondrocalcinosis was observed. To the best of our knowledge, this is the first report in Korea of GS with chondrocalcinosis. Antialdosterone therapy or magnesium supplementation is effective in preventing the progression of chondrocalcinosis; thus, early diagnosis and treatment of GS are important.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Potassium
/
Arthrite
/
Spironolactone
/
Vomissement
/
Chondrocalcinose
/
Diagnostic précoce
/
Alcalose
/
Syndrome de Gitelman
/
Maladies génétiques congénitales
/
Hypokaliémie
Type d'étude:
Etude diagnostique
/
Étude de dépistage
Limites du sujet:
Adulte
/
Femelle
/
Humains
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Journal of Rheumatic Diseases
Année:
2016
Type:
Article
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