Research Progress of the Relationship between the Expression of TAR DNA-binding Domain Protein 43 and Brain Injury / 法医学杂志
Journal of Forensic Medicine
;
(6): 289-292, 2017.
Article
Dans Chinois
| WPRIM
| ID: wpr-984895
ABSTRACT
TAR DNA-binding domain protein 43 (TDP-43) is a highly conserved and widely expressed nuclear protein. Nowadays, the expression of TDP-43 can be found in most neurodegenerative diseases such as Alzheimer's disease, which makes it become a neurodegenerative disease associated marker protein. From the current research status at homeland and abroad, and around the relationship between the expression of TDP-43 and brain injury, this article emphatically probes into the specific expression and function of TDP-43 in acute and chronic brain injury based on the knowledge of its biological characteristics, which aims to explore the feasibility for determining the cause of death and the injury and disability situations by TDP-43 in forensic pathology.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Lésions encéphaliques
/
ADN
/
Protéines de liaison à l'ADN
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Forensic Medicine
Année:
2017
Type:
Article
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