Application of High-throughput Sequencing in Researches of Cadaveric Microorganisms and Postmortem Interval Estimation / 法医学杂志
Journal of Forensic Medicine
;
(6): 475-481, 2018.
Article
Dans Chinois
| WPRIM
| ID: wpr-984959
ABSTRACT
Necrobiome is the main factor causing the cadaver decomposition. Studying the microbial succession during decomposition is one of the main tasks of forensic microbiology. The interactive relationships among cadaver, environment and microorganisms are complicated. The microbial succession study relies on macroscopic monitoring of community composition and the diversity change in each decomposition stage. With the maturity and development of high-throughput sequencing (HTS), the structure and diversity of microbial communities in different environments have been successively revealed. A new breakthrough to explore the cadaveric microorganisms has been opened as well. It has become the research hotspots in forensic microbiology to reveal the microbial succession in the process of cadaver decomposition and to interpret the essence of various decomposition phenomena by using HTS, which can provide a new reference for postmortem interval (PMI) estimation. The present paper reviews studies on PMI estimation by using cadaveric microorganism. Problems and application prospects of forensic microbiology studies are discussed on the basis of the current application of HTS technology in the exploration of microbial succession.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Modifications postmortem
/
Autopsie
/
Bactéries
/
Cadavre
/
Séquençage nucléotidique à haut débit
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Forensic Medicine
Année:
2018
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS