Research Progress on Chiral Separation Methods and Toxic Effects of Methamphetamine Enantiomers / 法医学杂志
Journal of Forensic Medicine
;
(6): 337-343, 2019.
Article
Dans Anglais
| WPRIM
| ID: wpr-985019
ABSTRACT
Methamphetamine (MAMP) is a kind of amphetamine-type stimulants (ATS) which contains one chiral carbon atom in its structure. Therefore a pair of enantiomers, S-(+)-MAMP and R-(-)-MAMP exist. R type and S type methamphetamines possess similar physicochemical properties, but has largely different pharmacological and toxic effects. S-(+)-MAMP is the main component of addictive drug "Ice" at present, seriously affecting human health and public safety. The separation analysis and mechanism of toxic effects discussions on MAMP are the current research focuses. This paper reviews the research progress of separation analysis methods and toxic effects of methamphetamine enantiomers to provide reference for forensic study and forensic practice.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Stéréoisomérie
/
Détection d'abus de substances
/
Stimulants du système nerveux central
/
Métamfétamine
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Journal of Forensic Medicine
Année:
2019
Type:
Article
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