Research progress in reversing multidrug resistance in colorectal cancer / 国际肿瘤学杂志
Journal of International Oncology
; (12): 42-46, 2023.
Article
Dans Zh
| WPRIM
| ID: wpr-989518
Responsable en Bibliothèque :
WPRO
ABSTRACT
Multidrug resistance impacts negatively upon the curative effect of chemotherapy and prognosis in colorectal cancer. There is a growing body of studies trying to develop drugs to overcome multidrug resistance against its common targets, including ATP-binding cassette proteins, metabolic enzymes, apoptotic genes, signaling pathways and genetic material, among which P-glycoprotein inhibitors and drugs disrupting DNA are deeply developed. Developing new inhibitors or combining existing inhibitors with conventional treatment are hopeful ways to overcome multidrug resistance in colorectal cancer.
Texte intégral:
1
Indice:
WPRIM
langue:
Zh
Texte intégral:
Journal of International Oncology
Année:
2023
Type:
Article