Severe disseminated intravascular coagulation complicated by acute renal failure during pregnancy / 世界急诊医学杂志（英文）

ABSTRACT

@#Disseminated intravascular coagulation (DIC) is a clinical syndrome caused by various etiologies and characterized by systemic activation of blood coagulation, leading to vessel thrombosis, organ dysfunction, and severe bleeding.[1] DIC represents a life-threatening condition that is the endpoint of uncontrolled systemic activation of the disease. Once it enters the stage of malignant DIC, the patient’s death becomes unavoidable. DIC always occurs as a secondary disorder and is commonly associated with postpartum hemorrhage, followed by hypertensive disorders, acute fatty liver of pregnancy, sepsis, and amniotic fluid embolism (AFE).[2] In clinical obstetrics, DIC often occurs during delivery or postpartum, while cases of prenatal acute DIC as the first manifestation are uncommon. Patients with DIC have higher rates of multiple organ dysfunction syndrome, including acute renal failure (ARF), respiratory failure, and disturbance of consciousness.