Reactivation of Chagas disease in a heart transplant patient infected by sylvatic trypanosoma cruzi discrete typing unit I
Rev. Soc. Bras. Med. Trop
;
52: e20180512, 2019. tab
Artigo
em Inglês
| LILACS
| ID: biblio-1013317
ABSTRACT
Abstract Heart transplantation is an effective treatment for Chagas disease patients with severe cardiomyopathy. However, Trypanosoma cruzi reactivation is of great concern. The T. cruzi parasite is classified into six discrete typing units (DTUs identified as TcI-TcVI). It is unknown whether there is an association between T. cruzi genetic lineages and the different clinical manifestations of the disease. We report the case of a 51-year-old man who received a heart transplantation and presented with a reactivation of the disease. The molecular characterization of the parasite showed that the reactivation was related to specific infection by a DTU I (TcISYL) parasite.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Tripanossomicidas
/
Cardiomiopatia Chagásica
/
Transplante de Coração
/
Imunossupressores
/
Nitroimidazóis
Tipo de estudo:
Estudo prognóstico
Limite:
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
Medicina Tropical
Ano de publicação:
2019
Tipo de documento:
Artigo
País de afiliação:
Colômbia
Instituição/País de afiliação:
Instituto Nacional de Salud/CO
/
Universidad Nacional de Colombia/CO
Similares
MEDLINE
...
LILACS
LIS