Etanercept in erythema nodosum leprosum
An. bras. dermatol
;
92(4): 575-577, July-Aug. 2017. graf
Artigo
em Inglês
| LILACS
| ID: biblio-1038255
ABSTRACT
Abstract: One of the biggest challenges in treating leprosy is the control of reaction events. Patients with lepromatous leprosy may present reaction type II, or erythema nodosum leprosum, during treatment, and this reaction can remain in a recurrent form after being released from the hospital, requiring the use of thalidomide and/or prednisone for long periods of time, in turn increasing the risk of side effects. Two reports of the use of antiTNF to treat erythema nodosum leprosum were found in the literature. A good response was found after an assay with infliximab and etanercept. This study reports on a patient with lepromatous leprosy and recurrent reaction, controlled by using etanercept and a 10-month follow-up, with the interruption of thalidomide and the maintenance of prednisone at 10 mg/day.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Hanseníase Virchowiana
/
Anti-Inflamatórios não Esteroides
/
Eritema Nodoso
/
Etanercepte
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
An. bras. dermatol
Assunto da revista:
Dermatologia
Ano de publicação:
2017
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Santa Casa de Misericórdia do Rio de Janeiro/BR
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