Human sapovirus GI. 2 and GI. 3 from children with acute gastroenteritis in northern Brazil
Mem. Inst. Oswaldo Cruz
;
114: e180574, 2019. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-1040626
ABSTRACT
Human sapoviruses (HSaV) are considered important causative agents of acute gastroenteritis in humans worldwide. However, knowledge of the genetic characteristics of the whole genome of HSaV in Brazil is limited. Here we report the complete genome sequences of six HSaVs GI.2 and two GI.3 strains obtained from children with acute gastroenteritis in the Northern region of Brazil. Next generation sequencing was used to obtain the full genome and molecular characterization of the genome was performed. Phylogenetic analysis of the genome was also performed. Only one complete HSaV GI.2 genome characterization in the country precedes that of the present study. This is the first complete genome sequence of genotype GI.3 in Brazil. The data obtained in this investigation can contribute to the augmentation of the database on the molecular diversity of HSaVs strains circulating in Brazil, and to the improvement of current typing protocols.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Infecções por Caliciviridae
/
Sapovirus
/
Gastroenterite
Limite:
Criança
/
Humanos
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2019
Tipo de documento:
Artigo
País de afiliação:
Brasil
/
Estados Unidos
Instituição/País de afiliação:
Blood Systems Research Institute/US
/
Faculdade de Medicina do ABC/BR
/
Instituto Adolfo Lutz/BR
/
Laboratório Central de Saúde Pública do Tocantins/BR
/
Universidade Federal de Tocantins/BR
/
Universidade Federal do Pará/BR
/
Universidade de São Paulo/BR
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