Alterations induced in the ileum of mice upon inoculation with different species of Leishmania: a preliminary study
Rev. Soc. Bras. Med. Trop
;
51(4): 537-541, July-Aug. 2018. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-1041471
ABSTRACT
Abstract INTRODUCTION:
Leishmania species cause skin, mucosal, and disseminated lesions. We studied the effects of three Leishmania species on ileal morphology in mice.METHODS:
BALB/c mice were intraperitoneally inoculated with Leishmania (Leishmania) amazonensis, Leishmania (Viannia) braziliensis, and Leishmania (Leishmania) major (4 animals/group). After 72h, the ilea were collected and histologically processed.RESULTS:
Following inoculation, the goblet cell and intraepithelial lymphocyte populations increased, while Paneth cell number and crypt width decreased. In addition, enterocyte size, villi height, and mucosa, submucosa, and muscular tunic thickness increased.CONCLUSIONS:
Leishmania modified the quantity of cells in and morphology of mice ilea.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Leishmaniose
/
Íleo
/
Leishmania
/
Camundongos
Limite:
Animais
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
Medicina Tropical
Ano de publicação:
2018
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Universidade Estadual de Maringá/BR
Similares
MEDLINE
...
LILACS
LIS