Therapeutic failure after regimen with artemether-lumefantrine combination therapy: a report of three cases in Benin City, Nigeria
Rev. Soc. Bras. Med. Trop
;
52: e20190163, 2019.
Artigo
em Inglês
| LILACS
| ID: biblio-1041528
ABSTRACT
Abstract Artemisinin-based combination therapy (ACT) is recommended by the World Health Organization for the treatment of uncomplicated malaria. Currently, there appears to be a downward trend in the efficacy of ACT in some parts of sub-Saharan Africa because some patients have been positive for Plasmodium parasite 3 days after artemether-lumefantrine treatment. We reported three cases of possible parasite resistance to artemether-lumefantrine therapy. All subjects had complete parasite clearance when treated with other antimalarial drugs. This observation necessitates the urgent need to re-evaluate artemether-lumefantrine medication in Nigeria since it is one of the most commonly used ACT drug.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Malária Falciparum
/
Combinação Arteméter e Lumefantrina
/
Antimaláricos
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
Medicina Tropical
Ano de publicação:
2019
Tipo de documento:
Artigo
País de afiliação:
Nigéria
Instituição/País de afiliação:
Bethel Faith Medical Centre/NG
/
Michael and Cecilia Ibru University/NG
/
University of Benin/NG
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