Genotypes of clinical varicella-zoster virus isolates from Manaus, Brazil
Rev. Soc. Bras. Med. Trop
;
52: e20180166, 2019. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-1041564
ABSTRACT
Abstract INTRODUCTION: Vaccination against varicella-zoster virus (VZV) has been effective and safe in countries that routinely administer the vaccine. Brazil began universal VZV vaccination in 2013. This study aimed to identify VZV genotypes present in Manaus, Brazil prior to widespread immunization. METHODS: Vesicular lesions or cerebral-spinal-fluid samples were collected from patients diagnosed with VZV, herpes zoster, or meningitis/encephalitis. DNA was extracted, amplified, and sequenced. RESULTS: Half the isolates were clade-5 viruses and the remaining were divided between the European clades 1 and 3. CONCLUSIONS: This study provides insights into the circulating VZV genotypes in Manaus prior to widespread vaccination.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Herpesvirus Humano 3
/
Infecção pelo Vírus da Varicela-Zoster
Limite:
Adolescente
/
Adulto
/
Idoso
/
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
Medicina Tropical
Ano de publicação:
2019
Tipo de documento:
Artigo
País de afiliação:
Brasil
/
Estados Unidos
Instituição/País de afiliação:
Centers for Disease Control and Prevention/US
/
Fundação de Medicina Tropical Dr. Heitor Vieira Dourado/BR
/
Hospital Universitário Getúlio Vargas/BR
/
Universidade do Estado do Amazonas/BR
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