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Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelation
Wissam, Zam; Samer, Housheh.
  • Wissam, Zam; Al-Andalus University for Medical University. Faculty of Pharmacy. Department of Analytical and Food Chemistry. Tartous. SY
  • Samer, Housheh; Al-Andalus University for Medical University. Faculty of Pharmacy. Department of Pharmaceutical Chemistry and Quality control. Tartous. SY
Braz. J. Pharm. Sci. (Online) ; 55: e00261, 2019. tab, graf
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1055323
ABSTRACT
The objective of the current study was to encapsulate flaxseed oil extracted from finely grounded flaxseed powder and determined for its fatty acids content by GC/FID. Ionotropic gelation method was used to form beads containing 40% flaxseed oil with vitamin E being used as an antioxidant agent. The study employed calcium chloride solution as crosslinking agent with a combination of sodium alginate and salep. The effect of polymer concentrations and calcium chloride concentration on the morphology, entrapment efficiency and oil release was studied. The encapsulation efficiency reached 93.46 ± 0.064% using 0.6% of salep and 2% sodium alginate with 0.3M calcium chloride gelling solution. In SGF medium, the matrix released only about 28.56% of the entrapped flaxseed oil after 2 hours. The rest of the oil then released in the SIF medium, continuing for up to 5 h to release 99.32% of the oil.


Texto completo: DisponíveL Índice: LILACS (Américas) Idioma: Inglês Revista: Braz. J. Pharm. Sci. (Online) Assunto da revista: Farmacologia / Terapˆutica / Toxicologia Ano de publicação: 2019 Tipo de documento: Artigo País de afiliação: Síria Instituição/País de afiliação: Al-Andalus University for Medical University/SY

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Texto completo: DisponíveL Índice: LILACS (Américas) Idioma: Inglês Revista: Braz. J. Pharm. Sci. (Online) Assunto da revista: Farmacologia / Terapˆutica / Toxicologia Ano de publicação: 2019 Tipo de documento: Artigo País de afiliação: Síria Instituição/País de afiliação: Al-Andalus University for Medical University/SY