A consensus document for the clinical management of invasive fungal diseases in pediatric patients with hematologic cancer and/or undergoing hematopoietic stem cell transplantation in Brazilian medical centers
Braz. j. infect. dis
;
23(6): 395-409, Nov.-Dec. 2019. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-1089309
ABSTRACT
ABSTRACT In the present paper we summarize the suggestions of a multidisciplinary group including experts in pediatric oncology and infectious diseases who reviewed the medical literature to elaborate a consensus document (CD) for the diagnosis and clinical management of invasive fungal diseases (IFDs) in children with hematologic cancer and those who underwent hematopoietic stem-cell transplantation. All major multicenter studies designed to characterize the epidemiology of IFDs in children with cancer, as well as all randomized clinical trials addressing empirical and targeted antifungal therapy were reviewed. In the absence of randomized clinical trials, the best evidence available to support the recommendations were selected. Algorithms for early diagnosis and best clinical management of IFDs are also presented. This document summarizes practical recommendations that will certainly help pediatricians to best treat their patients suffering of invasive fungal diseases.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Neoplasias Hematológicas
/
Infecções Fúngicas Invasivas
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo de etiologia
/
Guia de Prática Clínica
/
Estudo de rastreamento
Limite:
Criança
/
Humanos
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Braz. j. infect. dis
Assunto da revista:
Doenças Transmissíveis
Ano de publicação:
2019
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Grupo em Defesa da Criança com Câncer/BR
/
Hospital Infantil Darcy Vargas/BR
/
Hospital Infantil Sabará/BR
/
Hospital Samaritano de São Paulo/BR
/
Hospital Santa Marcelina TUCA/BR
/
Hospital das Clínicas de Curitiba/BR
/
Hospital das Clínicas de Porto Alegre/BR
/
Instituto de Oncologia Pediátrica/BR
/
Pro-Imagem medicina diagnóstica Ribeirão Preto/BR
/
Santa Casa de Belo Horizonte/BR
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