Development of an enzyme-linked immunosorbent assay for diagnosis of human herpesvirus-7 infection
Rev. Soc. Bras. Med. Trop
;
53: e20190181, 2020. graf
Artigo
em Inglês
| LILACS
| ID: biblio-1092205
ABSTRACT
Abstract INTRODUCTION:
Human herpesvirus (HHV)-7 establishes a latent infection during the lifetime of the host and can reactivate after the primary infection, leading to lytic replication in immunosuppressed patients.METHODS:
This study aimed to develop an enzyme-linked immunosorbent assay (ELISA) to identify HHV-7 serum antibodies and compare its performance with that of an indirect immunofluorescence assay (IFA).RESULTS:
Serum samples (n=102) were tested by IgG-IFA and by ELISA. IFA and ELISA showed IgG-positive results in 77 and 73 samples, respectively. Qualitative concordance of 96% was demonstrated between the two techniques.CONCLUSIONS:
ELISA may be useful to diagnose HHV-7 infection.
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Imunoglobulina G
/
Herpesvirus Humano 7
/
Infecções por Roseolovirus
/
Anticorpos Antivirais
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
/
Pesquisa qualitativa
Limite:
Humanos
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
Medicina Tropical
Ano de publicação:
2020
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
Fundação Hermínio Ometto/BR
/
Instituto Butantan/BR
/
Universidade Federal dos Vales do Jequinhonha e Mucuri/BR
Similares
MEDLINE
...
LILACS
LIS